Idiopathic Dilated Cardiomyopathy: Cellular and Molecular by H. R. Figulla (auth.), Prof. Dr. med. Hans-Reiner Figulla,

By H. R. Figulla (auth.), Prof. Dr. med. Hans-Reiner Figulla, Prof. Dr. med. Reinhard Kandolf, Prof. Bruce McManus Ph.D., M.D. (eds.)

The newest advancements in molecular biology have broadened our realizing of the pathogenesis of idiopathic dilated cardiomyopathy (IDC). during this booklet, written by means of recognized specialists, a accomplished overviewof IDC is given, together with simple mobile and molecular recommendations, virology, immunology, cardiac receptors and ionic channels, contractility abnormalities, microcirculation, and oxygen provide in cardiac hypertrophy. information on uncomplicated learn are supplemented by means of result of new medical trials in IDC and the most recent info at the epidemiology of the disorder. should you have an interest within the sickness, the ebook summarizes development in all significant fields.

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Fuster V, Gersh Bl, Giuliani ER, Tajik Al, Brandenburg RO, Frye RL (1981) The natural history of idiopathic dilated cardiomyopathy. Am J Cardiol 47:525-531 25. Gavazzi A, Lanzarini L, Cornalba C, Desperati M, Raisaro A, Angoli L, De Servi S, Specchia G (1984) Dilated (congestive) cardiomyopathy. G Ital Cardiol 14:492-498 26. Gavazzi A, De Maria R, Caroli A, Di Lenarda A, Veritti U, Miani D, Sinagra G, Luvini M, Ometto R, Borgia M, Ciaccheri W, Campana C, Graziano G, Lanzarini L, Gronda E, Camerini F (1990) Complex ventricular arrhythmias in dilated cardiomyopathy: a multicenter italian experience.

4 rJ) 0123456 No. 1 o 24 48 72 96 120 144 168 192 Months Years Fig. la-d. Examples of survival curves with constant and progressive slopes in the course of follow-up. a Kuhn et al. [45]; b Lengyel and K6keny [50]; c Gavazzi et al. [25]; d Komajda et al. [44] F. Camerini et al. ,;--. i. 1: VI 040 > '~. (104) (72) (56) (51) (45) (37) (35) (31) (24) (19) (16) Years o 0~'~~2~~~;~~~6~~~8--~1b b b Follow up (years) 00 ,. ,. '. ,.. i. ~ ~ 40 (J) 20 o c o " , , 1 · . · , 1 •••• 1 . . , •• 10 20 30 40 50 Interval quarters Fig.

Shirey EK, Proudfit WL, Hawk WA (1980) Primary myocardial disease. Correlation with clinical findings, angiographic and biopsy diagnosis. Am Heart J 99:198 85. Solis E, Kaye MP (1986) The registry of the international society for heart transplantation: third official report - June 1986. J Heart Transplant 5:2 86. Torp A (1981) Incidence of congestive cardioymopathy. In: Goodwin JF, Hjalmarson A, Olsen EGJ (eds) Congestive cardiomyopathy. Hossle, Molndal, p 18 87. Unverferth DV, Magorien RD, Moeschberger ML, Baker BT, Fetters JK, Leier CV (1984) Factors influencing the one year mortality of dilated cardiomyopathy.

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