Carotenoid Cleavage Products by Peter Winterhalter, Susan E. Ebeler

By Peter Winterhalter, Susan E. Ebeler

The significance of carotenoid cleavage reactions in vegetation and animals has been recognized because the early 1900s. those early reviews established that ?-carotene was once degraded to shape nutrition A, that is very important for human future health and performs a severe position in imaginative and prescient. in spite of the fact that, the particular biochemical mechanisms concerned, and the enzyme answerable for B-carotene cleavage in vivo, weren't pointed out until eventually the mid- to late-1990s (Wolf 1995; Woggon 2000, von Lintig and Vogt) (1-3). additionally within the overdue 1990's, comparable carotenoid cleavage enzymes have been pointed out in vegetation and located to be vital within the construction of plant hormones (Schwartz et al., 1997) (4) and aroma compounds. those enzymatic cleavage reactions had just recently been came upon on the time of the final ACS symposium on Carotenoid Derived Aroma Compounds (Winterhalter and Rouseff, 2001) (5) and basically 3 papers on enzymatic creation of apo-carotenoids have been awarded. considering the fact that that point, the sphere has exploded and the significance of carotenoid cleavage enzymes in organic reactions has been well-established. the present ACS Symposium on Carotenoid Cleavage items used to be designed to spotlight those contemporary discoveries, targeting the genetic and molecular biology of carotenoid cleavage enzymes, the significance of apo-carotenoids in taste and aroma of end result, greens, and wines, and the expanding curiosity in biotechnological facets of apo-carotenoid production.
These court cases should be a worthwhile connection with nutrition scientists, biochemists, and analytical chemists who're on the vanguard of realizing the chemistry, research, and bioactivity of carotenoids and their cleavage items

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13), rats were fed lycopene as part of their daily diet for 50 days, followed by a radioactive dose of [14C] labeled lycopene on day 51. Afterwards, radioactivity (as measured by scintillation counting) was observed in both the feces and the urine up to 168 hrs. post-dosing. While a majority of the excreted radioactivity was observed in feces, ~3% of the radioactivity observed was in urine (13). A similar study was recently conducted in humans, where [14C] labeled lycopene was fed to two healthy subjects and samples of blood plasma, urine, skin, and breath CO2 were collected (14).

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