Basic and Clinical Aspects of Malignant Melanoma by Anthony P. Albino (auth.), Larry Nathanson M.D. (eds.)

By Anthony P. Albino (auth.), Larry Nathanson M.D. (eds.)

Where do you start to seem for a contemporary, authoritative article at the analysis or administration of specific malignancy? The few normal oncology textbooks are commonly outdated. unmarried papers in really expert journals are informative yet seldom complete; those are extra frequently initial stories on a really restricted variety of sufferers. yes basic journals often post reliable in-depth stories of melanoma subject matters, and released symposium lectures are usually the simplest overviews on hand. regrettably, those stories and vitamins seem sporadically, and the reader can by no means make certain whilst a subject of unique curiosity may be coated. melanoma therapy and study is a sequence of authoritative volumes which target to satisfy this want. it's an try and determine a serious mass of oncology literature protecting nearly all oncology issues, revised often to maintain the assurance brand new, simply on hand on a unmarried library shelf or by way of a unmarried own subscription. now we have approached the matter within the following style. First, via dividing the oncology literature into particular subdividions comparable to lung melanoma, genitouri­ nary melanoma, pediatric oncology, and so on. moment, via asking eminent experts in every one of those parts to edit a quantity at the particular subject on an annual or biannual foundation. each one subject and tumor kind is roofed in a quantity showing often and predictably, discussing present prognosis, staging, markers, all types of remedy modalities, simple biology, and more.

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As discussed above, we closely monitored a 21 number of cytoplasmic and cell-surface antigens for qualitative and/or quantitative changes. Table 6 shows the results of serological and biochemical tests for expression of these antigens in infected and noninfected melanocytes. One of the earliest detectable changes after infection with Ha-MSV or Ki-MSV was the induction of Class II major histocompatibility gene products (la antigens). Melanocytes showed strong expression of la antigens within three to five days after infection with these transforming viruses.

112. 113. 114. 115. 116. 117. 118. 119. 120. 121. 38 growth in vitro by monoclonal anti-GDJ-ganglioside antibody. Cancer Research 44:806-810, 1984. Seyfried TN, Yu RK: Ganglioside GDJ: structure, cellular distribution, and possible function. Mol Cell Biochem 68:3-10, 1985. Houghton AN, Mintzer D, Cordon-Cardo C, Welt S, Fliegel B, Vadhan S, Carswell E, Melamed MR, Oettgen HF, Old LJ: Mouse monoclonal IgG J antibody detecting GDJ ganglioside: A phase I trial in patients with malignant melanoma. Proc Nat!

Phenotypic characteristics of metastatic cells 1. 2. 3. 4. 5. 6. 7.

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