Active Surveillance for Localized Prostate Cancer: A New by Laurence Klotz M.D., F.R.C.S.C. (auth.), Laurence Klotz

By Laurence Klotz M.D., F.R.C.S.C. (auth.), Laurence Klotz (eds.)

Active Surveillance for Localized Prostate melanoma: a brand new Paradigm for scientific administration will function an invaluable source for physicians facing, and drawn to, this advanced and evolving department of prostate melanoma administration. The publication can also be of curiosity to scientifically literate sufferers and their households. the amount presents an advent to the concept that of lively surveillance in oncology quite often and prostate melanoma in particular. the first concentration is to supply a finished advisor to the administration of sufferers on surveillance. the quantity covers the numerous complexities and nuances to this strategy together with, sufferer choice, possibility evaluate, how you can triumph over 'cancer hysteria' while counseling sufferers, picking acceptable triggers for intervention, use of PSA kinetics and MR imaging details, method and frequency of biopsies, secondary prevention interventions, and the relative roles of surveillance and focal therapy.

Show description

Read or Download Active Surveillance for Localized Prostate Cancer: A New Paradigm for Clinical Management PDF

Best clinical books

Purine Metabolism in Man—II: Physiology, Pharmacology, and Clinical Aspects

The research of gouty arthritis has supplied a standard assembly floor for the study pursuits of either the elemental scientist and the clinician. The curiosity of the chemist in gout all started 1776 with the isolation of uric acid from a concretion of the urinary tract by means of the Swedish chemist SCHEELE. an analogous substance used to be for this reason extracted from a gouty tophus by way of the British chemist WOLLASTONE in 1797 and a part century later the reason for the deposits of sodium urate In such tophi was once traced to a hyperuricemia within the serum of gouty sufferers by way of the British doctor Alfred Baring GARROD who had additionally acquired education within the chemical laboratory and used to be hence a fore-runner of lots of brand new clinician-investigators.

Idiopathic Dilated Cardiomyopathy: Cellular and Molecular Mechanisms, Clinical Consequences

The most recent advancements in molecular biology have broadened our knowing of the pathogenesis of idiopathic dilated cardiomyopathy (IDC). during this e-book, written via famous specialists, a entire overviewof IDC is given, together with simple mobile and molecular options, virology, immunology, cardiac receptors and ionic channels, contractility abnormalities, microcirculation, and oxygen provide in cardiac hypertrophy.

Free Radicals in Diagnostic Medicine: A Systems Approach to Laboratory Technology, Clinical Correlations, and Antioxidant Therapy

A global Syaposiua on loose Radicals in Diagnostic drugs was once co-sponsored through the kingdom college of recent York at Buffalo, Roswell Park melanoma Institute, and the Upstate manhattan component of the yank organization of scientific Chemistry. The topic was once "A structures method of Laboratory expertise, medical Correlations And Antioxidant remedy.

Appropriate Dose Selection — How to Optimize Clinical Drug Development

Optimum dose individualization has turn into extra very important in enhancing medical efficacy and security, given the variety in drug reaction, e. g. , as a result of concurrent health problems or co-medications. consequently, the position of optimum dose discovering in early medical drug improvement with a view to maximize profitable scientific use is emphasised.

Additional resources for Active Surveillance for Localized Prostate Cancer: A New Paradigm for Clinical Management

Example text

Lu-Yao GL, Albertsen PC, Moore DF, et al. Outcomes of localized prostate cancer following conservative management. JAMA. 2009 Sep 16;302(11):1202–9. 26. Stattin P, Holmberg E, Johansson JE, Holmberg L, Adolfsson J, Hugosson J. Outcomes in localized prostate cancer: National Prostate Cancer Register of Sweden follow-up study. J Natl Cancer Inst. 2010 Jul 7;102(13):950–8. 19 27. Bill-Axelson A, Holmberg L, Filen F, et al. Radical prostatectomy versus watchful waiting in localized prostate cancer: the Scandinavian prostate cancer group-4 randomized trial.

12 (Fig. 3a). By focusing our efforts on a cohort with a high percentage of intermediate-risk patient’s all treated with surgery as curative, we optimized our ability to accurately discriminate patients with indolent vs. aggressive disease. 47 (Fig. 3b). , AR and Ki67) in the discrimination of disease progression risk among intermediate-grade prostate cancers. The investigation of AR in diagnostic prostate tissue both as an indicator for innate tumor aggressiveness and association with response to hormonal therapy has been studied for over 25 years.

Perspectives on utilizing unique features of microfluidics technology for particle and cell sorting. JALA. 2009;14:331–40. 52. Wang S, Owens GE, Tseng HR. Nano “fly paper” technology for the capture of circulating tumor cells. Methods Mol Biol. 2011;726:141–50. 53. Stott SL, Lee RJ, Nagrath S, Yu M, Miyamoto DT, Ulkus L, Inserra EJ, Ulman M, Springer S, Nakamura Z, Moore AL, Tsukrov DI, Kempner ME, et al. Isolation and characterization of circulating tumor cells from patients with localized and metastatic prostate cancer.

Download PDF sample

Rated 4.54 of 5 – based on 7 votes

About the Author

admin